Monoclonal gammopathy of undetermined significance (MGUS)
MGUS is a non-cancerous condition where there is an increased amount of abnormal protein in the blood and/or urine.
In MGUS, abnormal plasma cells in the bone marrow produce an abnormal antibody, known as paraprotein.
MGUS doesn’t cause any symptoms and is usually picked up during a routine blood or urine test. People diagnosed with MGUS don’t require any treatment apart from regular follow-up by their doctor to have their protein levels checked. Over time a small number of people with MGUS may go on to develop myeloma . The risk of developing myeloma is extremely low with only 1% of people with MGUS developing myeloma each year.
For more detailed information about MGUS you can view and download our fact sheet here
